Supply, delivery and installation of Cyclotron and Radio-synthesis Laboratory to the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology (RSSPMCOR) in Tashkent, Uzbekistan.
UNOPS
Supply, delivery and installation of Cyclotron and Radio-synthesis Laboratory to the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology (RSSPMCOR) in Tashkent, Uzbekistan.
Request for quotation
Reference:
RFQ/2023/46787
Beneficiary countries:
Uzbekistan
Registration level:
Basic
Published on:
31-Oct-2023
Deadline on:
25-Jan-2024 07:00 (GMT 0.00)
Description
This RFQ refers to the Supply, delivery and installation of Cyclotron and Radio-synthesis Laboratory to the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology (RSSPMCOR) in Tashkent, Uzbekistan The requirement consists of the following 11 items divided into 2 lots:
Lot #1:
Item #1: Cyclotron;
Item #2: Synthesis Modules;
Item #3: Hot Cells and Dispensers;
Item #4: Quality Control Lab;
Item #5: Radiation Monitoring and Dosimetry Equipment;
Item #6: Consumables and Accessories;
Item #7: Cyclotron Vault Door;
Item #8: UPS (option 1);
Item #8*: UPS (option 2);
Item #9: Chiller;
Item #10: Furniture.
Lot #2:
Item #1:Target & Synthesis.
Note to Bidders:
Bidders are allowed to quote prices for one or more lots identified in this tender. However, the Bidders must offer 100% of the quantities specified for each lot. Evaluation will be done separately for each lot. UNOPS reserves the right to vary the quantities of lots or remove a lot, and award multiple contracts for each lot.
IMPORTANT NOTE: Interested vendors must respond to this tender using the UNOPS eSourcing system, via the UNGM portal. In order to access the full UNOPS tender details, request clarifications on the tender, and submit a vendor response to a tender using the system, vendors need to be registered as a UNOPS vendor at the UNGM portal and be logged into UNGM. For guidance on how to register on UNGM and submit responses to UNOPS tenders in the UNOPS eSourcing system, please refer to the user guide and other resources available at: https://esourcing.unops.org/#/Help/Guides
Lot #1:
Item #1: Cyclotron;
Item #2: Synthesis Modules;
Item #3: Hot Cells and Dispensers;
Item #4: Quality Control Lab;
Item #5: Radiation Monitoring and Dosimetry Equipment;
Item #6: Consumables and Accessories;
Item #7: Cyclotron Vault Door;
Item #8: UPS (option 1);
Item #8*: UPS (option 2);
Item #9: Chiller;
Item #10: Furniture.
Lot #2:
Item #1:Target & Synthesis.
Note to Bidders:
Bidders are allowed to quote prices for one or more lots identified in this tender. However, the Bidders must offer 100% of the quantities specified for each lot. Evaluation will be done separately for each lot. UNOPS reserves the right to vary the quantities of lots or remove a lot, and award multiple contracts for each lot.
IMPORTANT NOTE: Interested vendors must respond to this tender using the UNOPS eSourcing system, via the UNGM portal. In order to access the full UNOPS tender details, request clarifications on the tender, and submit a vendor response to a tender using the system, vendors need to be registered as a UNOPS vendor at the UNGM portal and be logged into UNGM. For guidance on how to register on UNGM and submit responses to UNOPS tenders in the UNOPS eSourcing system, please refer to the user guide and other resources available at: https://esourcing.unops.org/#/Help/Guides
This tender has been posted through the UNOPS eSourcing system. / Cet avis a été publié au moyen du système eSourcing de l'UNOPS. / Esta licitación ha sido publicada usando el sistema eSourcing de UNOPS. Vendor Guide / Guide pour Fournisseurs / Guíra para Proveedores: https://esourcing.unops.org/#/Help/Guides
First name:
N/A
Surname:
N/A
This procurement opportunity integrates considerations for at least one sustainability indicator. However, it does not meet the requirements to be considered sustainable.
Prevention of pollution
Environmental
The tender contains sustainability considerations for the prevention of polluting emissions to air, solid waste to land and discharges to water.
Examples:
EMS, waste management and wastewater management.
| Link | Description | |
|---|---|---|
| https://esourcing.unops.org/#/Help/Guides | UNOPS eSourcing – Vendor guide and other system resources / Guide pour fournisseurs et autres ressources sur le système / Guía para proveedores y otros recursos sobre el sistema |
42201601
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Medical magnetic resonance imaging MRI stationary units
New amendment added #7: The RFQ has been further amended as follows: Deadline for the submission of quotations is extended till 25 January 2024.
Edited on:
16-Jan-2024 12:54
Edited by:
webservice@unops.org
New clarification added: Please, be informed that the Deadline for the RFQ Submission has been extended for two calendar days, that is, until 25.01.2024 07:00 UTC due to the system maintenance.
Edited on:
16-Jan-2024 04:57
Edited by:
webservice@unops.org
New clarification added: Q92: Reference is made to the requirement Lot 1 Item 6 Line 28 “Bidder must be provide all required consumables to cover analysis of 10 batches. Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? A92: The consumables can be in any form subject that includes all the needed materials to complete the quality control of the isotopes.
Edited on:
05-Jan-2024 10:59
Edited by:
webservice@unops.org
New clarification added: Q91: Reference is made to the requirement Lot 1 Item 6 Line 27 “Bidder must be provide all required consumables to cover analysis of 10 batches of 68Ga, 89Zr and 64Cu each production.” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? A91: The consumables can be in any form subject that includes all the needed materials to complete the quality control of the isotopes.
Edited on:
05-Jan-2024 10:57
Edited by:
webservice@unops.org
New clarification added: Q90: Reference is made to the requirement Lot 1 Item 6 Line 26 “Bidder shall provide all required consumables to produce 5 batches of 68Ga DOTATOC/DOTANOC/PSMA, production of each is separate for testing and validation.” Please clarify, what do you mean by "all necessary consumables"?Are these some ready-made kits? Or a list of individual items that are formed into a set? A90: The consumables can be in any form subject that includes all the needed materials to complete the quality control of the isotopes.
Edited on:
05-Jan-2024 10:56
Edited by:
webservice@unops.org
New clarification added: Q89: Reference is made to the requirement Lot 1 Item 6 Line 25 “Bidder shall provide all required consumables to produce 5 batches of 11 CO2 for testing and validation.” Please clarify, what do you mean by "all necessary consumables"?Are these some ready-made kits? Or a list of individual items that are formed into a set? A89:The consumables can be in any form subject that includes all the needed materials to complete the quality control of the isotopes.
Edited on:
05-Jan-2024 10:54
Edited by:
webservice@unops.org
New clarification added: Q88: Reference is made to the requirement Lot 1 Item 6 Line 22 “Bidder must be provide all required consumables to cover 5 batches of 13NH4 production. Each batch will require to fill min 25 pcs of sterile vials.” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? Please clarify what volume of vials needed and if there any additional requirements for the vials? A88:The consumables can be in any form subject that includes all the needed materials to complete the packaging of the isotopes. Closed vials of 10 ml volume (or any equivelant combination).
Edited on:
05-Jan-2024 10:52
Edited by:
webservice@unops.org
New clarification added: Q87: Reference is made to the requirement Lot 1 Item 6 Line 21 “Bidder must be provide all required consumables to cover 5 batches of 68Ga, 89Zr and 64Cu each production. Each batch will require to fill min 10 pcs of sterile vials.” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? Please clarify what volume of vials needed and if there any additional requirements for the vials? A87: The consumables can be in any form subject that includes all the needed materials to complete the packaging of the isotopes. Closed vials of 10 ml volume (or any equivelant combination)
Edited on:
05-Jan-2024 10:51
Edited by:
webservice@unops.org
New clarification added: Q86: Reference is made to the requirement Lot 1 Item 6 Line 20 “Bidder shall provide all required consumables to produce 5 batches of 68Ga DOTATOC/DOTANOC/PSMA, production of each is separate for testing and validation.” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? A86: The consumables can be in any form subject that include all the needed materials to complete the packaging of the isotopes.
Edited on:
05-Jan-2024 10:49
Edited by:
webservice@unops.org
New clarification added: Q85: Reference is made to the requirement Lot 1 Item 6 Line 19 “Bidder shall provide all required consumables to produce 5 batches of 11 CO2 for testing and validation.” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? A85: The consumables can be in any form subject that include all the needed materials to complete the packaging of the isotopes.
Edited on:
05-Jan-2024 10:47
Edited by:
webservice@unops.org
New clarification added: Q84: Reference is made to the requirement Lot 1 Item 6 Line 17 “Bidder must be provide all required consumables to cover 30 batches of FDG production. Each batch will require to fill min 25 pcs of sterile vials.” Please clarify what volume of vials needed and if there any additional requirements for the vials? A84: Closed vials of 10 ml volume (or any equivelant combination).
Edited on:
05-Jan-2024 10:46
Edited by:
webservice@unops.org
New clarification added: Q83: Reference is made to the requirement Lot 1 Item 6 Line 12 “Bidder must be provide all required consumables to cover 5 batches of 68Ga, 89Zr and 64Cu each production.” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? A83: The consumables can be in any form subject that includes all the needed materials to complete the synthesis of the isotopes.
Edited on:
05-Jan-2024 10:44
Edited by:
webservice@unops.org
New clarification added: Q82:Reference is made to the requirement Lot 1 Item 6 Line 10 “Bidder must be provide all required consumables to cover 5 batches of 13NH4 production” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? A82: Since the synthesis/packaging/quality control workflow for each bidder/manufacturer is unique, it is difficult to define the needed consumables per manufacturer (to provide the needed bid flexibility). The consumables can be in any form subject that includes all the needed materials to complete the production of the isotopes into vials.
Edited on:
05-Jan-2024 10:42
Edited by:
webservice@unops.org
New clarification added: Q81: Reference is made to the requirement Lot 1 Item 6 Line 9 “Bidder must be provide all required consumables to cover 5 batches of 68Ga, 89Zr and 64Cu each production.” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? A81: Since the synthesis/packaging/quality control workflow for each bidder/manufacturer is unique, it is difficult to define the needed consumables per manufacturer (to provide the needed bid flexibility). The consumables can be in any form subject that includes all the needed materials to complete the production of the isotopes into vials.
Edited on:
05-Jan-2024 10:40
Edited by:
webservice@unops.org
New clarification added: Q79: Reference is made to the requirements in Lot 1 Item 6 lines 7 “Bidder shall provide all required consumables to produce 5 batches of 11 CO2 for testing and validation.” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? A79: Since the synthesis/packaging/quality control workflow for each bidder/manufacturer is unique, it is difficult to define the needed consumables per manufacturer (to provide the needed bid flexibility). The consumables can be in any form subject that includes all the needed materials to complete the production of the isotopes into vials.
Edited on:
05-Jan-2024 10:37
Edited by:
webservice@unops.org
New clarification added: Q80: Reference is made to the requirement in Lot 1 Item 6 Line 8 “Bidder shall provide all required consumables to produce 5 batches of 68Ga DOTATOC/DOTANOC/PSMA. Production of each is separate for testing and validation.” Please clarify, what do you mean by "all necessary consumables"? Are these some ready-made kits? Or a list of individual items that are formed into a set? A80: Since the synthesis/packaging/quality control workflow for each bidder/manufacturer is unique, it is difficult to define the needed consumables per manufacturer (to provide the needed bid flexibility). The consumables can be in any form subject that includes all the needed materials to complete the production of the isotopes into vials.
Edited on:
05-Jan-2024 10:10
Edited by:
webservice@unops.org
New clarification added: Q78. RFQ-2023-46787 Section IV Draft Contract for Goods, 2.3. Warranty and After-sales Services: “At least 95% uptime (full functioning) in a year, i.e. 347 days out of 365 days, will be guaranteed by the Supplier within the warranty period. In the event that the item supplied has been malfunctioning for more than five percent (5%) of one single year of the warranty period, i.e. more than 18 natural days in one single year, the Supplier shall extend the warranty period for a double (2x) duration of the equipment’s downtime.” Could you please clarify what do you mean by 95% uptime (full operation) per year? A78. The 95% uptime means that the Radioisotope production/quality control should be available 347 days per year (347 corresponding to 95% of 365). Therefore the workflow should not go down for more than 18 days in a calendar year. The service personnel should service and maintain the machine to honor this percentage. The schedule of requirements and the Draft contract has listed all exceptions in the calculation of the downtime.
Edited on:
26-Dec-2023 08:33
Edited by:
webservice@unops.org
New clarification added: Q77. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item3, S/N2: “Class C Double vertical hot cells with greater than 100 mm lead thickness to the above mentioned modules. The inside of the hot-cell should be totally made of high quality stainless steel (314). It should have requisite inlets for gases, air, vacuum, water etc. The hot cell should be compliant with current GMP.” and RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item3, S/N4: “The thickness of the lead shielding of the box on all sides is not less than 100 mm”. Could you please advise if the total lead thickness of hot cells should be at least 200 mm (100mm at line 2 + 100 mm at line 4)? A77. No, it is 100 mm only, S/N2 was a general explanation of the requirement and S/N4 is to evaluate the shielding thickness.
Edited on:
26-Dec-2023 08:28
Edited by:
webservice@unops.org
New clarification added: Q76. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item5, S/N8: “Climate condition of cyclotron vault” could you please advise what does climate condition of cyclotron vault stand for?A76. Climate conditions refer to the humidity and temperature in the vault. This will be monitored and transmitted automatically during cyclotron runs.
Edited on:
26-Dec-2023 08:24
Edited by:
webservice@unops.org
New amendment added #6: The RFQ has been further amended as follows: Deadline for clarification requests is extended till 05 January 2024.Deadline for the submission of quotations is extended till 22 January 2024.To update the requirements based on the requested clarifications, the document titled "RFQ-2023-46787_Section_III_Returnable Bidding Forms_Form D_Technical Quotation Form_REV3_12DEC23 is hereby replaced with the further updated document titled "RFQ-2023-46787_Section_III_Returnable Bidding Forms_Form D_Technical Quotation Form_REV4_15DEC23".RFQ Particulars have been updated in order to:Extend the Quotation validity period from 90 to 180 days;Update the Evaluation Method Details due to removal of lot-based evaluation;Update the Advance payment details with additional requirement for written justification to explain the need for the advance payment, itemize the amount requested, and provide a time-schedule for utilization of the said amount.
Edited on:
16-Dec-2023 16:56
Edited by:
webservice@unops.org
New clarification added: A75. Due to the insufficient time available to clarify the changes made to the documentation and the upcoming holidays, we ask you to extend the Clarificaton period by another 15 days and the deadline for submission of documents for 25 more days from the currently designated dates respectively. A75. UNOPS agrees to accommodate the request for extension of deadlines one last time. The RFQ is amended to extend the deadline for Clarification requests till 05 January 2024 and the deadline for submission of bids till 22 January 2024.
Edited on:
16-Dec-2023 16:47
Edited by:
webservice@unops.org
New clarification added: Q74. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N E8: “Gamma Counter (Qty 1)” - Could you please advise which isotopes/products are planned to be analyzed? A74. The gamma counter should analyze 18F, 11C, 13N and 68Ga.
Edited on:
16-Dec-2023 16:44
Edited by:
webservice@unops.org
New clarification added: Q73. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N24: “Radioactivity detector for the required radiopharmaceuticals in Line 23” . Will they stay alone? Will those detectors require computers for control, or will they be connected to existing HPLC's?A73. S/N 23, 24 and 25 under Lot1, Item4 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” have been amended to address this point.
Edited on:
16-Dec-2023 16:35
Edited by:
webservice@unops.org
New clarification added: Q72. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N C: “Radiochemical fume hood for manipulation, with laminar air flow (Qty1)”. What is the purpose of this equipment? Are there any other compartment parts to be included, or only a shielded LAF Cabinet? A72. S/N 15, 16 and 17 under Lot1, Item4 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” are amended to address this point.
Edited on:
16-Dec-2023 16:28
Edited by:
webservice@unops.org
New clarification added: Q71. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N A: “Protective fume hood for handling”. Will this be a shielded Fume hood or Shielded LAF Cabinet? A71. Shielded LAF cabinet is required.
Edited on:
16-Dec-2023 16:23
Edited by:
webservice@unops.org
New clarification added: Q70. To make a door to a cyclotron bunker, could you please provide the following information: dimensions of the opening; sliding or swing doors; thickness of lead in the door (if available according to the “radiation shielding report” calculation), thickness of steel in the door (if available according to the “radiation shielding report” calculation), thickness of polyethylene and type of polyethylene in the door (if available according to the “radiation shielding report” calculation). A70. According to the Section II: Schedule of Requirements, Section II.2e - Designs and Drawings: “The awarded Contractor shall provide full shielding design for the cyclotron vault, control room, equipment room and synthesis lab. The awarded Contractor shall coordinate further with the construction company for advice on the design and workflow of the department" the door composition must be calculated within the shielding report that is within the scope of the bidder's responsiblities under this tender.
Edited on:
16-Dec-2023 16:11
Edited by:
webservice@unops.org
New clarification added: Q69. RFQ-2023-46787_Section_IV_Draft_Contract_for_Goods, Clause 3.4. has the following requirement: “Documents must arrive well in advance of goods. Contractor will be held responsible for any financial loss resulting from failure to comply with the above requirements. Payment will be effected within thirty (30) days of receipt of the above documents by this office.” Could you please clarify "well in advance of goods" in more detail?A69. The shipping documents are normally prepared in several copies. Whilst one set accompanies the cargo, other sets are sent by courier to the Consignee and the Notify Party as soon as the goods are shipped. These documents received in advance of goods' arrival are then used for preparation of customs clearance process. This is what is meant by "well in advance of goods".
Edited on:
16-Dec-2023 16:08
Edited by:
webservice@unops.org
New clarification added: Q68. Due to the disruptions in the global supply chain processes that still continue around the world after the pandemic, it is not appropriate to implement the FCA and DPU delivery due dates reflected in Section II.3: Delivery requirements. This section needs to be updated by taking into account the production cycle and product delivery times specified by the official manufacturers of the products. Depending on the manufacturer’s declarations of production and delivery terms, we request that the periods specified in the contract be extended to 24± 4 months.A68. If you cannot implement the indicated delivery requirements of the RFQ, please tick the "No" box in the respective Returnable Bidding Form's table and provide the details of your proposed delivery schedule articulating the associated timelines for each step within the relevant supply chain.
Edited on:
16-Dec-2023 16:03
Edited by:
webservice@unops.org
New clarification added: Q67. RFQ Particilculars state that "Advance Payment may be allowed for up to USD 500,000 or 25% of the total Contract Price, whichever is the lesser. For a project of this scale, it is not possible to manage the project properly by taking 500k USD as advance payment? We would like to get your feedback whether the following payment schedule would be acceptable: "30% in advance, 25% after 120 days, 25% when Cyclotron and Hotcell are ready for delivery, 10% after installation completed for Cyclotron and Hotcell, 10% after completion of commissioning. A67. Please note that it is against the United Nations policy to pay for the goods in advance, except where normal, commercial practice or the best interests of UNOPS so require. We have now further clarified in the Tender Particulars that "Any request from a bidder for advance payment within or outside the above indicated limits, shall be justified in writing and shall be submitted with the bidder's price proposal. This justification shall explain the need for the advance payment, itemize the amount requested, and provide a time-schedule for utilization of the said amount. UNOPS does not guarantee automatic approval of the advance payment for the requested amount in the case of contract award. Final amount of advance payment, if approved, and relevant conditions shall be agreed upon with the awarded supplier prior to the signature of contract."
Edited on:
16-Dec-2023 15:52
Edited by:
webservice@unops.org
New amendment added #5: The RFQ has been further amended in order to accommodate the latest requested changes by the Beneficiary.1) To reflect the changes requested by the Beneficiary, the solicitation documents have been amended as follows: a) The document titled "RFQ-2023-46787_Section_III_Returnable_Bidding_Forms_Form C_Price Schedule Form" is replaced with the updated document titled "RFQ-2023-46787_Section_III_Returnable_Bidding_Forms_Form C_Price Schedule Form_REV1_12DEC23".b) The document titled "RFQ-2023-46787_Section_III_Returnable Bidding Forms_Form D_Technical Quotation Form_REV2_05DEC23 " is replaced with the updated document titled "RFQ-2023-46787_Section_III_Returnable Bidding Forms_Form D_Technical Quotation Form_REV3_12DEC23".c) The document titled "RFQ-2023-46787_Section_IV_Draft_Contract_for_Goods_REV3_05DEC23" is replaced with the updated document titled "RFQ-2023-46787_Section_IV_Draft_Contract_for_Goods_REV4_12DEC23".2) To allow time for the prospective bidders to review the changes and ask questions the deadline for clarification requests is extended till 15 December 2023, 12:00 PM Tashkent time (UTC +5hrs).
Edited on:
13-Dec-2023 13:47
Edited by:
webservice@unops.org
New clarification added: Q66. RFQ-2023-46787 Section II: Schedule of Requirements, Section II.2b - Manufacturer & Supplier Certification, Requirements for distributors: “Have all the licenses and authorizations required under national legislation of the country of operation issued by the national regulatory authority or other relevant entity; Could you please advise what kind of documents are required for this requirement? Will it be enough to submit ISO 9001 only? A66. Distributors must present ISO 9001 or equivalent, along with the national license and authorisation for import, distribution, installation and maintenance of particular medical equipment type. This licence must be accompanied by special authorisation related to import of radioisotopes. However, both licences can be obtained after the contract signature, whereas ISO 9001 or equivalent must be presented at the time of bid submission. For detailed information please visit the links provided herein:https://lex.uz/acts/13868; https://lex.uz/docs/1464242; https://lex.uz/docs/1506110
Edited on:
12-Dec-2023 19:25
Edited by:
webservice@unops.org
New clarification added: Q65. FQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/NE18:“Water-bath (Qty 1)”. Could you please check the difference with this ultrasonic cleaner? Will the Thermo Scientific Precision Model TSGP02 work? There are two major differences between ultrasonic and water-bath: 1) The ultrasonic is able to maintain water temperature up to 69 °C while the water-bath (Thermo which is possible to order by size 2 to 20 L) can do 100 °C. 2) The ultrasonic has sweep frequency by 40 Khz while the water-bath does not have this option. A65. Any equipment that will fulfills the workflow of the lab will be accepted.
Edited on:
12-Dec-2023 19:23
Edited by:
webservice@unops.org
New clarification added: Q64. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N 35: “Calibration sources for dose calibrator”. The calibration sources are not included in the pcat. Customer needs to purchase it. A64. All the requirements must be fulfilled by the bidder, i.e. the calibration sources must be supplied too.
Edited on:
12-Dec-2023 19:22
Edited by:
webservice@unops.org
New clarification added: Q63. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N 34: “Minimum 300 L, temp. Between 8 to 19 degrees Celsius or better”. Could you please check the range of temperature? A63. S/N E10 and S/N34 under Lot1, Item4 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” are amended to address this point.
Edited on:
12-Dec-2023 19:17
Edited by:
webservice@unops.org
New clarification added: Q62. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N E8: “Gamma Counter (Qty 1)”. Is it a Hand Held Radiation Monitoring device?A62. Please see A14 for the description of this item.
Edited on:
12-Dec-2023 19:15
Edited by:
webservice@unops.org
New clarification added: Q61. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N25: “Lead shielding for radioactivity detector (3 pcs.)”. Could you please clarify why 3 detectors are needed and what kind? A61. S/N25 under Lot1, Item4 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
12-Dec-2023 19:13
Edited by:
webservice@unops.org
New clarification added: Q60. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N24: “Additional radioactivity detector (Qty 3)”. Could you please clarify why 3 detectors are needed and what kind? A60. S/N24 under Lot1, Item4 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
12-Dec-2023 19:11
Edited by:
webservice@unops.org
New clarification added: Q59. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N15 the following specifications: “The cyclotron must be capable of delivering a beam of 300 µA or more. Beam current to be adjustable and stable at any current settings.” Could you please provide details on the purpose and reason for such a strict request for this parameter? It is still not completely clear on what basis this request was formed. Unfortunately, in case this parameter is not changed we will not be able to participate in this tender due to deliberate restriction as a manufacturer. A59. This requirement unfortunately cannot be changed. This requirement is set by the beneficiary considering their future increase in production rate.
Edited on:
12-Dec-2023 19:09
Edited by:
webservice@unops.org
New clarification added: Q58. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N 10 has the following specifications: Capable of producing of minimally the following isotopes with liquid, gas or solid targets (unless otherwise defined) * Current: 18F, 11C, 13N, 68Ga, * Future: 124I, 64Cu, 89Zr. Question: In this item, 15O has been removed, but there is a reference to 15O on a separate sheet, "Lot 2 Item 1 -Target & Synthesis". Kindly check and consider modification of the line as follows: “Capable of producing of minimally the following isotopes with liquid, gas or solid targets (unless otherwise defined) * Current: 18F, 11C, 13N, 15O, 68Ga, * Future: 124I, 64Cu, 89Zr “.A58. S/N 10 under Lot1, Item1 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
12-Dec-2023 19:07
Edited by:
webservice@unops.org
New clarification added: Q57. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item3, S/N24: “Sequences for synthesis of the above-mentioned radiopharmaceuticals should be detailed”. Could you please explain in more detail what is requested by this line? A57. Additional details on the workflow of the synthesis of each isotope is required.
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12-Dec-2023 18:58
Edited by:
webservice@unops.org
New clarification added: Q56. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item3, S/N23 Is semi-automatic dispenser acceptable? A56. Semi-automatic dispenser is not acceptable.
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12-Dec-2023 18:57
Edited by:
webservice@unops.org
New clarification added: Q55. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item3, S/N16. We can allow interlocked mechanical collection into the drawing system, please let us know, will be it considered as a significant discrepancy from the requirements? A55. Any proven and compliant solution that fits the purpose of the required specification will not be rejected.
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12-Dec-2023 18:54
Edited by:
webservice@unops.org
New clarification added: Q54. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item3, S/N14. We are in position to interlock the opening with a Geiger Muller detector, please let us know, will be it considered as a significant discrepancy from the requirements? A54. Any proven and compliant solution that fits the purpose of the required specification will not be rejected.
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12-Dec-2023 18:53
Edited by:
webservice@unops.org
New clarification added: Q53. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item3. It seems that S/N2 conflicts with S/N4. Could you please check? A53. Both lines refer to minimum 100mm lead thickness. There is no conflict.
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12-Dec-2023 18:51
Edited by:
webservice@unops.org
New clarification added: Q52. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item6, could you please clarify if the consumables for dispensing units are included? A52. S/N A2 under Lot1, Item6 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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12-Dec-2023 18:49
Edited by:
webservice@unops.org
New clarification added: Q51. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N21: “Width not less than 140 cm.”. Could you please clarify if it is an external or internal dimension? A51. S/N 21 under Lot1, Item4 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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12-Dec-2023 18:47
Edited by:
webservice@unops.org
New clarification added: Q50. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item3, S/N24: “Sequences for synthesis of the above-mentioned radiopharmaceuticals should be detailed.” Is this specification related to synth modules? Could you please clarify if this specification can be removed?A50. Yes, this specification is related to the synthesis modules and it cannot be removed. The bidder is required to attach the needed explanatory document.
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12-Dec-2023 18:45
Edited by:
webservice@unops.org
New clarification added: Q49. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item6: “if the 30 batchs, 5 batches means 30 kits and 5 kits of consumables? One kit is for one production. But there's also consumables for packing and for quality control. Could you please advise what the actual demand quantity for consumables for FDG production and others is? A49. S/N A3 under Lot1, Item6 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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12-Dec-2023 18:44
Edited by:
webservice@unops.org
New clarification added: Q48. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item6, S/N4: “Two air Compressors of appropriate capacity and pressure to continuously supply purified dry air (purity ≥99,995)”. Synthetic air cannot be measured with a purity of 99.995 as it is a mixture of gasses (nitrogen (78.1%), oxygen (20.9%) and other impurities (1%). It is not quite clear what purity should be ≥99.995. Does it mean a complete system of air purification and dehumidification to the required parameters? Or should it be two compressors to supply air at the required pressure? Will a centralized air treatment system be used in the hospital? Additional equipment is required for purification and collection of purified air. Would you be so kind as to clarify what is expected?A48. S/N 4 under Lot1, Item6 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” are amended to address these points.
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12-Dec-2023 18:42
Edited by:
webservice@unops.org
New clarification added: Q47. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item6, S/N1,2,3: “ Hydrogen in cylinders with, purity ≥99.995 total volume not less than: 150 l”, “Helium in cylinders, purity ≥99.9995 total volume not less than: 150 l”, “Nitrogen in cylinders, ≥99,995 total volume not less than: 150 l”. 1) Could you please advise if medical license/certificate required for the gas provided? 2) Could you please advise what volume of gas and at what pressure is required? A47. 1) Yes, supporting documents are needed as a proof of the contents of the supplied gas. 2) S/N 1, 2, 3 under Lot1, Item6 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” are amended to address this question.
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12-Dec-2023 18:40
Edited by:
webservice@unops.org
New clarification added: Q46. As we are facing some difficulty while filling the 4th subtopic of Supplier Information Form, Trading Status (Type of Organization) of the Main Bidder, we kindly ask for your help as the system just allows us to enter a numeric answer and we can not move forward with the filling of the rest of the form. We would like to choose / state ourselves as an “Incorporated Company”. A46. Please enter numbers based on your type of organization as per the following reference: a) is 1;b) is 2;c) is 3;d) is 4;e) is 4; f) is 5; g) is 6.
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12-Dec-2023 18:39
Edited by:
webservice@unops.org
New clarification added: Q45. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N35: “Reproducibility of Ga 68 fusion not less than: 96%”. Could you pelase clarify what standards are being referenced? A45. S/N35 under Lot1, Item2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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12-Dec-2023 18:34
Edited by:
webservice@unops.org
New clarification added: Q44. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N30: “Maximum input activity of C 11 is not less than: 14 Ci.”. Could you please clarify what standards are being referenced? A44. S/N30 under Lot1, Item2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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12-Dec-2023 18:32
Edited by:
webservice@unops.org
New clarification added: Q43. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N26: “Radiochemical purity of C 11 is not less than: >99%.” What standards are being referenced? Could you please modify this requirement as follows: “Radiochemical purity of C 11 is not less than: 95%”? A43. S/N26 under Lot1, Item2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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12-Dec-2023 18:30
Edited by:
webservice@unops.org
New clarification added: Q42. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N21: “It has to be certified with ISO 13485, and software must comply with 21 CFR Part 11. It must follow the GAMP5 guidelines”. A42. S/N21, 32 and 42 under Lot1, Item2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” are amended to address this point.
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12-Dec-2023 18:04
Edited by:
webservice@unops.org
New clarification added: Q41. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N19: “Residual activity after synthesis is not more than: 1,0 %”. This parameter depends on the half-life. Could you please remove these requirements to avoid misunderstanding? A41. S/N19 under Lot1, Item2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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12-Dec-2023 18:02
Edited by:
webservice@unops.org
New clarification added: Q40. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N18: “Radiochemical purity of FDG not less than: 98%”.What standards are being referenced? Could you please modify the line as following: “Radiochemical purity of FDG not less than: 95%”? A40. S/N18 under Lot1, Item2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
12-Dec-2023 18:00
Edited by:
webservice@unops.org
New clarification added: Q39. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N12: “One synthesis module for labeling of Ga68, Lu177, Ac225, Y90 that will be placed in a dedicated hot lab in same floor (Floor -1) at hospital building.” Could you please remove Lu177, Ac225, and Y90 as they are not consistent with Item 1 specifications? A39. This requirement can not be changed. This specification was already clarified with the MOH where they provided the following justification: * Lu177: source of supply: - Institute of Nuclear Physics of the Republic of Uzbekistan, in the form of Lu177-chloride. * Ac225: provision through purchases from foreign manufacturers. * Y90: provision through purchases from foreign manufacturers. Information: in practice, one type of synthesis module is used for labeling Ga68, Lu177, Ac225, Y90.
Edited on:
12-Dec-2023 17:56
Edited by:
webservice@unops.org
New clarification added: Q38. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N3: “Capability of 4 FDG Synthesis within one cassette, or 2 FDG Synthesis within one cassette (In this case two of the same module has to be supplied with appropriate dimensions to install two of them in the same hot cell box).” Since multiple syntheses are difficult to control the quality of reagents, it is recommended a single synthesis device is approved. Could you please modify the specification as following: “Capability of 4 FDG Synthesis within one cassette, or 2 FDG Synthesis within one cassette (In this case two of the same module has to be supplied with appropriate dimensions to install two of them in the same hot cell box) or single FDG synthesis in one cassette?” A38. This requirement cannot be changed. Please, provide the proper justification and we will take it into consideration during the evaluation process.
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12-Dec-2023 17:54
Edited by:
webservice@unops.org
New clarification added: Q37. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N34: “No manual tuning is required when changing targets. Continuous target position feedback automatically corrects beam on target alignment during irradiation.” Could you please modify the specification as follows: “Automatic(preferably) or manual tuning is required when changing targets. Continuous target position feedback automatically or manually correction of the beam on target alignment during irradiation.”? A37. This requirement cannot be changed. This requirement is set by the beneficiary considering their future production plans.
Edited on:
12-Dec-2023 17:47
Edited by:
webservice@unops.org
New clarification added: Q36. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N33: “Automatic selection/switching of targets (along with automatic parameters upload) without manual intervention inside the bunker.” Is it possible to limit this item to 64Cu, 68Ga, 89Zr or delete this specification because it is not consistent with the specifications of Lot1 Item2 Synthesis Modules and Lot1 Item3 Hot Cells and Dispensers? A36. This requirement cannot be changed. There is a need for an automated system in the overall workflow between the vault and the synthesis lab.
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12-Dec-2023 17:42
Edited by:
webservice@unops.org
New clarification added: Q35. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N20: “Control console with one computer workstation and a printer. This workstation aims to provide a centralized automated fully controlled scheme to record and archive parameter information. Remote access through third party software to the control console has to be allowed for authorized staff.” Is it possible to limit this item to 64Cu, 68Ga, 89Zr or delete this specification because it is not consistent with the specifications of Lot1 Item2 Synthesis Modules and Lot1 Item3 Hot Cells and Dispensers? A35. This requirement cannot be changed. There is a need for an automated system in the overall workflow between the vault and the synthesis lab.
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12-Dec-2023 17:40
Edited by:
webservice@unops.org
New clarification added: Q34. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N15: “The cyclotron must be capable of delivering a beam of 300 µA or more. Beam current to be adjustable and stable at any current settings.” The cyclotron 150µA but can produce the yields listed in No.11-14. The cost in terms of building construction tends to increase in proportion to the higher amperage, for example, the walls must be thicker. It is strongly requested that no restrictions be placed on this item. Due to limitations as for the Manufacturer, could you please modify the specifications as follows: “The cyclotron must be capable of delivering a beam of at least 150 µA or more. Beam current to be adjustable and stable at any current settings.”A34. This requirement can not be changed. This requirement is set by the beneficiary considering their future production plans.
Edited on:
12-Dec-2023 17:36
Edited by:
webservice@unops.org
New clarification added: Q33. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N10: “Capable of producing of minimally the following isotopes with liquid, gas or solid targets (unless otherwise defined) * Current: 18F, 11C, 13N, , 68Ga, * Future: 124I, 64Cu, 89Zr”. In fact, it is not listed in Lot1 Item2 Synthesis Modules and Lot1 Item3 Hot Cells and Dispensers. Theoretically, production of 124I with cyclotron is quite few, while not only solid target but also a purification unit and a hot cell are needed for initial investment as well as expensive target materials for operation. Could you please remove this specification due to low outcome and high economical unprofitability? A33. S/N10 under Lot1, Item1 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” was already amended to address this point.
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12-Dec-2023 17:34
Edited by:
webservice@unops.org
New clarification added: Q32. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N9: “Variable energy: proton beam energy should be adjusted by user software for different radionuclides”. The cyclotron does not need to be equipped with an energy tuning function since it is tuned to the nuclides produced by the degrader target foil. Could you please remove this specification due to inapplicability? A32. S/N9 under Lot1, Item1 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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12-Dec-2023 17:31
Edited by:
webservice@unops.org
New clarification added: Q31. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N7: “Bombarding a target with protons.” There are 15O gas/water, 18FDOPA, etc. in the production nuclide, and utilizing Deuteron should allow it to be produced inexpensively and stably. Could you please modify the line as “Bombarding the targets with Protons and Deuterons”?A31. S/N7 under Lot1, Item1 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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12-Dec-2023 17:29
Edited by:
webservice@unops.org
New amendment added #4: The RFQ has been further amended in order to: 1) To reflect the changes in the requirements, the document titled "RFQ-2023-46787_Section_II_Schedule_of_Requirements _REV1_25NOV23" is hereby replaced with the updated document titled "RFQ-2023-46787_Section_II_Schedule_of_Requirements _REV2_05DEC23".2) To reflect the changes in the requirements, the document titled "RFQ-2023-46787_Section_III_Returnable Bidding Forms_Form D_Technical Quotation Form_REV1_25NOV23" is hereby replaced with the updated document titled "RFQ-2023-46787_Section_III_Returnable Bidding Forms_Form D_Technical Quotation Form_REV2_05DEC23".3) To reflect the changes, the document titled "RFQ-2023-46787_Section_IV_Draft_Contract_for_Goods_REV2_25NOV23" is hereby replaced with the updated document titled "RFQ-2023-46787_Section_II_Schedule_of_Requirements _REV3_05DEC23".4) Deadline for the submission of quotations is extended till 04 January 2024, 12:00 PM Tashkent time (UTC +5hrs).5) Deadline for clarification requests is extended till 10 December 2023, 12:00 PM Tashkent time (UTC +5hrs).
Edited on:
05-Dec-2023 13:13
Edited by:
webservice@unops.org
New clarification added: Q30. Reference is made to RFQ-2023-46787_Section_IV_Draft_Contract_for_Goods Section IV, ANNEX 3: Schedule of Requirements, 2.3. Warranty and After-sales Services reads as follows: "At least 95% uptime (full functioning) in a year, i.e. 347 days out of 365 days, will be guaranteed by the Supplier within the warranty period. In the event that the item supplied has been malfunctioning for more than five percent (5%) of one single year of the warranty period, i.e. more than 18 natural days in one single year, the Supplier shall extend the warranty period for a double (2x) duration of the equipment's downtime. Time required for customs clearance of a replacement part, if any, shall not be counted towards the downtime." Could you please consider reducing the uptime commitment to 80% considering the following rationale:1. 95% uptime is requested to be fulfilled by the bidder/contractor in Western countries, where the service infrastructure supported by a larger install base of equipment is in place. Unfortunately, Uzbekistan is not there at this stage having only 3 cyclotrons across the country and insufficiently developed infrastructure.2. Full functioning of a complex system, such as cyclotron and its accessories (SC, synthesis etc) is highly dependent not only on vendor/it's partner local presence, but also on qualification of end-user/hospital staff: local engineers, physicists and other users. Accordingly, adequate functioning of a whole system could be highly dependent on the reason not totally depending on manufacturer/it's service partner.3. Country specific technical problems, related with internet infrastructure, VPN and personal data protection may be negatively influencing the adequate service provision.4. Shortages of accessories and supplies related to logistics constraints these days. A30. As already shared in lastest revison of "RFQ-2023-46787_Section_IV_Draft_Contract_for_Goods_REV2_25NOV23", the items covered within the uptime is different between the warranty and the post-warranty contract. During the warranty, UNOPS and the beneficiary expect 95% and maybe better uptime as the systems are brand new. For the contract that might be signed upon expiration of the warranty, bidders are asked to provide a dedicated quote for the repair services and the 95% uptime. This will be part of the evaluation as we look to properly maintain the equipment and the workflow within a controlled financial framework. 1) When a bidder refers to service infrastructure, it is referring to its side of responsibility. The bidder/supplier should guarantee the beneficiary that all the required service infrastructure is available for the best service experience. UNOPS has mentioned that the customs/clearance is not counted within the dowtime. This means the downtime calculation is based on the service response time, troubleshooting time and shipment. The calculation method will be adjusted to include more details while maintaining controlled conditions. We cannnot tolerate any delay in the response time, troubleshooting and placing orders as this in the control of the bidder. 2) When UNOPS sets 95% uptime, it refers to the time the machine will be ready for operation. One main part of the bidder's duty is to train the staff to the needed level to be able to operate the cyclotron properly. *If the hospital operators are not properly operating the machine, they will malfunction the equipment and this will not count in the downtime, otherwise the machine will stay up and ready. * Qualification of local engineers should be the responsibility of the bidder. Normally, no hospital engineer should be eligible to work on equipment under warranty or service contract. Nevertheless, if the bidder wants any hospital engineer to be its first level support then this should be on the bidder's own responsibility.3) If the internet is down due to local reasons, this will not be counted into the downtime. We will amend this accordingly. 4) As mentioned in the draft contract, any local logistics delays will not count in the downtime. UNOPS will make it more clear in the upcoming amendment. As mentioned above, lack of accessories and supplies will not affect the uptime as this will be not controlled by the bidder and is subject to multiple milestones.
Edited on:
30-Nov-2023 04:51
Edited by:
webservice@unops.org
New amendment added #3: The RFQ has been further amended in order to: 1) To reflect the changes in the requirements, the document titled "RFQ-2023-46787_Section_II_Schedule_of_Requirements " is hereby replaced with the updated document titled "RFQ-2023-46787_Section_II_Schedule_of_Requirements _REV1_25NOV23".2) To reflect the changes in the requirements, the document titled "RFQ-2023-46787_Section_III_Returnable Bidding Forms_Form D_Technical Quotation Form" is hereby replaced with the updated document titled "RFQ-2023-46787_Section_III_Returnable Bidding Forms_Form D_Technical Quotation Form_REV1_25NOV23 ".3) To reflect the changes, the document titled "RFQ-2023-46787_Section_IV_Draft_Contract_for_Goods_REV_15NOV23" is hereby replaced with the updated document titled "RFQ-2023-46787_Section_IV_Draft_Contract_for_Goods_REV2_25NOV23".
Edited on:
29-Nov-2023 13:23
Edited by:
webservice@unops.org
New clarification added: Q29. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item5, S/N6: “Stack Monitoring Channel” and S/N7: “Stack Flow Meter channel”. If the system does not have a Stack Monitoring Channel and Stack Flow Meter channel, but able only to measure the dose rate of ionizing radiation from outside the stack will it be considered as a significant discrepancy from the requirements? A29. Stack monitoring provides the ability to determine the amount of radiation released from the facility ventilation exhaust where the isotopes are produced. The flowmeter will be used to measure the online flow rate in the exhaust stack to enable the conversion of measured radiation into concentration. Any alternatives that can provide those functions will be accepted.
Edited on:
29-Nov-2023 12:48
Edited by:
webservice@unops.org
New clarification added: Q28. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item5, S/N2: “Item 5 Lot #1, line 2. Could you please clarify what type of ionizing radiation should be measured? A28. It will be used to detect Gamma radiation, X-rays, and alpha and beta particles in the range of 0.1μSv/h – 10 mSv/h.
Edited on:
29-Nov-2023 12:46
Edited by:
webservice@unops.org
New clarification added: Q27. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N39: “The amount of Ga 68 obtained is not less than: 15 ml.”. Could you please clarify what tracer is considered? A27.S/N D under Lot 1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
29-Nov-2023 12:43
Edited by:
webservice@unops.org
New clarification added: Q26. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N37: “Residual activity after fusion not more than: 1.0%”. Could you please clarify how fusion and reproducibility are defined and what tracer is considered? A26. S/N D under Lot1, Item2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
29-Nov-2023 12:42
Edited by:
webservice@unops.org
New clarification added: Q25. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N36: “Radiochemical purity of Ga 68 not less than: 99.8%”. Could you please clarify how fusion and reproducibility are defined, and what tracer is considered? A25. S/N D under Lot 1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
29-Nov-2023 12:40
Edited by:
webservice@unops.org
New clarification added: Q24. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot 1, item 2, S/N35: “Reproducibility of Ga 68 fusion not less than: 96%”. Could you please clarify how fusion and reproducibility are defined and what indicator is considered? A24. S/N D under Lot 1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
29-Nov-2023 12:38
Edited by:
webservice@unops.org
New clarification added: Q23. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot 1, item 2, S/N34: “Unadjusted Ga 68 yield not less than: 74%”. Could you please specify what tracer is considered here? A23. S/N D under Lot 1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
29-Nov-2023 12:35
Edited by:
webservice@unops.org
New clarification added: Q22. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot 1, item 2, S/N28: “Automatic cassette cleaning after synthesis”. It is not recommended synthesis of methyl iodide or triflate on a cassette as the high-temperature gas phase method is superior in terms of specific activity, which is crucial for most C11-tracers. Could you please exclude this requirement? A22. S/N28 under Lot 1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
29-Nov-2023 12:33
Edited by:
webservice@unops.org
New clarification added: Q21. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot 1, item 2, S/N27: “Residual activity after synthesis no more than: 1.0%”. Could you please clarify the time after the end of synthesis by which this requirement should be met and whether it applies to a particular tracer, methyl iodide, or methyl triflate? A21. S/N27 under Lot 1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
29-Nov-2023 12:32
Edited by:
webservice@unops.org
New clarification added: Q20. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N26: “Radiochemical purity of C 11 is not less than: >99%.” Could you please advise what tracer is considered? A20. S/N26 under Lot1, Item2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
Edited on:
29-Nov-2023 12:30
Edited by:
webservice@unops.org
New clarification added: Q19. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot 1, item 2, S/N25: “Reproducibility of C11 synthesis no less than: 96%”. Could you please advise how the reproducibility is determined in this context and whether it relates to methyl iodide, methyl triflate, or a specific tracer? A19. S/N25 under Lot 1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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29-Nov-2023 12:19
Edited by:
webservice@unops.org
New clarification added: Q18. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item 2, S/N24: “Uncorrected C11 output no less than: 74%”. Could you please clarify which tracer is being considered here? A18. S/N24 under Lot1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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29-Nov-2023 12:15
Edited by:
webservice@unops.org
New clarification added: Q17. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2, S/N23: “The total time for preparing the system for operation and synthesis of C11 is no more than: 30 minutes”. Could you please clarify if you need a methylation system, a carbonylation or cyanation module? Does S/N23 refer to methyl iodine, methyl triflate, or a specific tracer? A17. S/N23 under Lot1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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29-Nov-2023 12:13
Edited by:
webservice@unops.org
New clarification added: Q16. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item 2, S/N17: “Reproducibility of FDG synthesis not less than: 96%”. Could you please clarify how the reproducibility is defined? A16. S/N17 under Lot1, Item2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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29-Nov-2023 12:10
Edited by:
webservice@unops.org
New clarification added: Q15. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item2 , S/N2: “Use of sterile disposable cassettes for the synthesis of radiopharmaceuticals (RP). The required cassettes and reagents should be supplied by a third party manufacturer(s)”. The cassette is not sterilized; instead, it is controlled for bioburden.This practice has been sufficient in all 70 countries where FASTlab has been utilized thus far and aligns with GMP requirements. Could you please amend the requirement to be either sterilized or bioburden controlled? A15. S/N2 under Lot1, Item 2 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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29-Nov-2023 12:06
Edited by:
webservice@unops.org
New clarification added: Q14. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N E8: “Gamma Counter”. Could you clarify what kind of device is considered? Is it Hand Held Rad Monitoring or Wipe Test Counter? A14. The gamma counter will be based in the “Quality control lab”, therefore a benchtop based gamma spectrometer with the analyzer software is required.
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29-Nov-2023 12:02
Edited by:
webservice@unops.org
New clarification added: Q13. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N27: “All needed chromatography columns/detectors should be supplied to detect all the mentioned radiopharmaceuticals (current and future)”. This range is very wide and uncertain. Could you please clarify the list of tracers? A13. S/N27 under Lot1, Item4 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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29-Nov-2023 11:54
Edited by:
webservice@unops.org
New clarification added: Q12. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item4, S/N23: “Minimum 2 columns for 18C with UV & radioactive detector“. Could you please clarify for what exact tracers the columns should be included? A12. S/N23 under Lot1, Item4 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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29-Nov-2023 11:52
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webservice@unops.org
New clarification added: Q11. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N15: “The cyclotron must be capable of delivering a beam of 300 µA or more. Beam current to be adjustable and stable at any current settings.” A current of 300 µA can be useful in theory only for producing very high activities for further distribution. It is difficult to manipulate with such high activities and they have increased radiation safety risks. Considering that 3 operating cyclotrons are already installed in Tashkent, there is no point in such high activities and current. Currently only one cyclotron (IBA KIUBE) at the market meets this requirement. The maximum available beam current for GE HealthCare PETtrace cyclotron is 160 µA, while PETtrace meets all the requirements for activity yields mentioned above. We ask to reduce the requirement to 160 µA." A11. This requirement can not be changed.
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29-Nov-2023 11:49
Edited by:
webservice@unops.org
New clarification added: Q10. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N13: “Productivity of 13NH4OH target for 20 min of irradiation is not less than 800 mCi of activity end of bombardment” it is recommended irradiation time for 13NH4OH target is 30 min. Could you please extend the requirement to 30 min? A10. S/N13 under Lot1, Item1 in the RFQ Section III - Returnable Bidding Forms, Form D “Technical Quotation Form” is amended to address this point.
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29-Nov-2023 11:47
Edited by:
webservice@unops.org
New clarification added: Q9. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N10: “Production of minimally the below specifications (18F, 11C, 13N, 15O, 68Ga, 124I, 64Cu, 89Zr) with respective liquid, gas or solid targets”. Could you please clarify whether the proposal should only include the 68Ga, 64Cu, 89Zr solid targets as currently stated or should the full 68Ga, 64Cu, 89Zr production technology be provided? In the case of a complete technology, this will require the addition of additional hot cells, as well as synthesis and purification modules, which will lead to a significant increase in the cost of the entire project. Currently these hot cells and synthesis modules are not specified in the Lot1, item 3 “Hot Cells and Dispensers” and Lot1, Item 2 “Synthesis Modules”.A9. Ga68 will be produced in a cyclotron. The use of a solid target in a cyclotron to produce 68Ga makes it possible to produce 89Zr and 64Cu in a cyclotron in the shortest possible time, since the equipment for the production (minting) of a solid target and the system for transporting it to the cyclotron are similar.
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29-Nov-2023 11:45
Edited by:
webservice@unops.org
New clarification added: Q8. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item1, S/N10: "Production of minimally the below specifications (18F, 11C, 13N, 15O, 68Ga, 124I, 64Cu, 89Zr) with respective liquid, gas or solid targets".Despite the theoretical possibility, the production of 124I in cyclotrons with energies less than 20 MeV is unjustified due to the high capital and operational cost of this technology, long production time (more than 6 hours), low yield of I124 (2-3 patients after 6 hours production cycle) in such cyclotrons and limited clinical application. In addition the technical specification of Lot1, item 3 “Hot Cells and Dispensers” does not include enough hot cells to implement the full production cycle. Also, Lot1, Item 2 “Synthesis Modules” does not include the requirements for modules for the synthesis of radiopharmaceuticals based on 124I. Considering the unique physical and chemical properties of this isotope, it is recommended to use a separate laboratory for its production to avoid contamination with other tracers. We recommend excluding 124I from the isotopes list. In case the 124I availability requirement is critical, could you please clarify whether the proposal should only include the 124I target as currently stated or the full 124I production technology should be provided? In case of a complete technology, this will require the addition of additional hot cells, as well as synthesis and purification modules, which will lead to a significant increase in the cost of the entire project.A8. 124I is not required at this stage, however, the cyclotron must have the full 124I production capacity.
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29-Nov-2023 11:40
Edited by:
webservice@unops.org
New clarification added: Q7. Reference is made to RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot 1, Item1, S/N8: "The energy of the accelerated particles is not less than: 18 MeV”. Could you please reduce this requirement to 16.5 MeV? A7. This requirement can not be changed.
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29-Nov-2023 11:34
Edited by:
webservice@unops.org
New clarification added: Q6.Could you please advise if there are any possibilities to attach a Word file with requests for clarifications? A6. All requests for clarifications should be sent through e-sourcing as a text.
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29-Nov-2023 11:31
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webservice@unops.org
New clarification added: Q5. In order to streamline the process for preparation of the technical and financial proposals please review and consider the options for adjusting the deadlines as outlined below: a) state the official publication date for the revised documents (with the modifications made according to the ""bidders specification change requests"") on the eSourcing platform after the request for clarification period ends b) set the deadline for the final submission of the technical and financial documents as 30 days after the date stated in the previous paragraph. c) Due to the extensive preparation and planning required for this tender, we kindly request that you consider and implement the changes listed above. A5. a) All officially published revised documents have the date of amendment and the version number of the document in the name of a document. Notification on all amendments i.e. new or revised documents uploaded, deadlines changed are available at the "Revisions" section of the RFQ b) bid submission deadline will be amended if it is required within a reasonable time frame.
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29-Nov-2023 11:22
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webservice@unops.org
New clarification added: Q4. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item7 could you please advise what protective properties are needed?A4. a) For shielding protection, the door composition should be based on the radiation shielding report and bunker design that is requested under this tender. b) For personal protection, the door should include: touchgaurds, photo sensors, emergency stop switch(s), sound and visual alerts while opening and closing.
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29-Nov-2023 11:08
Edited by:
webservice@unops.org
New clarification added: Q3. RFQ-2023-46787 Section III - Returnable Bidding Forms, Form D “Technical Quotation Form, Lot1, item9 could you please advise what cooling capacity in kW is needed?A3. The chiller must have sufficient capacity to support appropriate functioning of the entire cyclotron system for 24 hours 7 days a week.
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29-Nov-2023 11:05
Edited by:
webservice@unops.org
New clarification added: Q2: RFQ Section II: Schedule of Requirements, Section II.2a - Manufacturer’s Authorisation reads as follows: “Manufacturer’s Authorisation shall be required only for the major equipment. Supply of non-critical parts, consumables, reagents, etc. shall not require manufacturer’s authorisation”. Could you clarify whether the items 5, 6, 7, 8, 8*, 9 and 10 of the LOT1 are non-critical parts, and shall not require manufacturer’s authorization?A2: RFQ Section II.2a - Manufacturer’s Authorisation - is amended to address this point.
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29-Nov-2023 11:01
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webservice@unops.org
New amendment added #2: The RFQ has been amended in order to:1) upload amended Section IV: Draft Contract for Goods in DOCUMENTS section under the title "RFQ-2023-46787_Section_IV_Draft_Contract_for_Goods_REV_15NOV23" which introduces revision of clause "2.3 Warranty and After-sales Services" of the Annex3: Schedule of Requirements in red font.
Edited on:
17-Nov-2023 14:27
Edited by:
webservice@unops.org
New amendment added #1: The RFQ has been amended in order to: 1) upload the pre-bid meeting minutes in the Documents section of the RFQ2) change the requirement of the document "Form A: Joint Venture Partner Information Form" in the Checklist section of the RFQ from "Document is mandatory " to " Document is optional"
Edited on:
14-Nov-2023 12:56
Edited by:
webservice@unops.org
New clarification added: Q1: Is it still mandatory to submit Form A: Joint Venture Partner Information Form if a bidder does not intend or shall not enter into a joint venture with a company or companies in order to deliver goods and services requested in this RFQ?As per the checklist of the documents to be submitted with a bid it is "mandatory" A1: BIdder shall use and submit Form A: Joint Venture Partner Information Form only if it intends and shall enter into a joint venture with a company or companies in order to deliver goods and services stipulated in this RFQ, otherwise it is not required for submission. UNOPS will change the status of the document from "mandatory" to "optional" in the current RFQ.
Edited on:
06-Nov-2023 09:17
Edited by:
webservice@unops.org